Describe a function, mechanism, phenotype, or relationship in plain
language. CREATION measures that intent against the field and returns
the genome records that resonate with it — then carries the ones you
keep into a cell program.
Ready · results open directly to authoritative NCBI records
Start with a mechanism, not a keyword.
A full sentence about the biology ranks better than a gene name.
Results keep their identifiers and resolve to the authoritative NCBI
record wherever one exists.
50 ranked records loaded · continue through the field
0 targetsOne resonance set · one cell population · simultaneous perturbation
Cell program
Make the ranked field physical.
Every selected target is carried forward as one simultaneous
perturbation program. The cell population becomes the readout.
Resonance-ranked target set
No decomposition, no secondary ranking. The selected field keeps its order.
0 targets
Intervention design
Design the molecule field.
The selected cell program becomes the specification. CREATION retrieves
measured chemistry, generates analogs, predicts ADMET and target
activity, checks synthesis feasibility, then ranks the candidate field
in ARBITER. Generated structures and predictions stay hypotheses until
they are tested at the bench.
Design lane
Cell program
0 targets · cell line not specified
01 Target mapWaiting
02 Known chemistryWaiting
03 GenerationWaiting
04 ADMETWaiting
05 BindingWaiting
06 SynthesisWaiting
07 ARBITERWaiting
Ready · no candidate design has been run
The ranked biology becomes a chemical search space.Run the pipeline to populate it. Every stage executes in the local CREATION chemistry worker.